verstreken

LABORATORYOFNEURONALCOMMUNICATION

Neurons in our brain are organized in circuits and communicate using synaptic vesicles that release neurotransmitters upon fusion with the membrane.  We study neurotransmission in healthy and diseased neurons using fruit fly genetics and a variety of functional in vivo assays including electrophysiology, live imaging and electron microscopy with links to Parkinson’s disease, epilepsy and ALS.

6/2010   Patrik Verstreken receives an ERC Starting Grant

11/2011  We show that complex I dysfunction is a major culprit in pink1 mutants

9/2011   The Joung European Drosophila Investigators (JEDIs) take a flying start!

© Patrik Verstreken

8/2010   We show WSP activated by PI(4,5)P₂ regulates NMJ size independent from BMP signaling

3/2011   We characterize Skywalker that controls vesicle protein clearance at the synapse

4/2011   Our paper on

Skywalker makes

the cover of Cell

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10/2011   Elp3 acetylates the active zone protein BRP

Check out our video abstract

10/2011   We move into our new lab space at the health sciences campus Gasthuisberg Leuven

12/2011   Ine Maes obtains an IWT fellowship

12/2011   David Vanneste obtains an EMBO long term fellowship

1/2012  In collaboration we develop PiMP and show super resolution imaging on a confocal

5/2012  We find VitaminK₂ as a novel mitochondiral electron carrier that rescues pink1 mutants

Download the paper here