Publications

2012

Sven Vilain, Giovanni Esposito, Dominik Haddad, Onno Schaap, Mariya P. Dobreva, Melissa Vos, Stefanie Van Meensel, Vanessa A. Morais, Bart De Strooper and Patrik Verstreken. (2012). The yeast complex I equivalent NADH dehydrogenase rescues pink1 mutants. PLoS Genetics. 8: e1002456.

2011

Katarzyna Miśkiewicz, Liya E. Jose, André Bento-Abreu*, Marcus Fislage*, Ines Taes, Jarosław Kasprowicz, Jef Swerts, Stephan Sigrist, Wim Versées, Wim Robberecht and Patrik Verstreken. (2011). ELP3 controls active zone morphology by acetylating the ELKS family member Bruchpilot. Neuron. 72: 776-788. *equal contribution

Giovanni Esposito, Clara Fernandes and Patrik Verstreken. Synaptic vesicle trafficking and Parkinson’s disease. Developmental Neurobiology. doi: 10.1002/dneu.20916.

Valerie Uytterhoeven*, Sabine Kuenen*, Jaroslaw Kasprowicz*, Katarzyna Miskiewicz* and Patrik Verstreken. (2011). Loss of Skywalker reveals synaptic endosomes as sorting stations for synaptic vesicle proteins. Cell. 145: 117-132. *equal contribution

2010

Thang-Mahn Khong*, Ron L.P. Habets*, Jan Slabbaert and Patrik Verstreken. (2010). WASP is activated by phosphatidylinositol-4,5-bosphosphate to restrict synapse growth in a pathway parallel to bone morphogenetic protein signaling. Proceedings of the National Academy of Sciences. 107:17379-17384. *equal contribution

Erik Storkebaum, C.R. de Almodovar, M. Meens, S. Zacchigna, M. Mazzone, G. Vanhoutte, S. Vinckier, K. Miskiewicz, K. Poesen, D. Lambrechts, G.M. Janssen, G.E. Fazzi, Patrik Verstreken, J. Haigh, P.M. Schiffers, H. Rohrer, A. Van der Linden, J.G. De Mey and Peter Carmeliet (2010) Impaired Autonomic Regulation of Resistance Arteries in Mice With Low Vascular Endothelial Growth Factor or Upon Vascular Endothelial Growth Factor Trap Delivery. Circulation. 122:273-281.

Brett H. Graham, Zhihong Li, Erminio P. Alesii, Patrik Verstreken, Cynthia Lee, Jennifer Wang and William J. Craigen (2010) Neurologic dysfunction and male infertility in drosophila porin mutants: A new model for mitochondrial dysfunction and disease. Journal of Biological Chemistry. 285:11143-11153.

Bruno A. Bergmans, S. Ali M. Shariati, Ron L. Habets, Patrik Verstreken, Luc Schoonjans, Ulrike Müller, Carlos G. Dotti and Bart De Strooper. (2010). Neurons generated from APP/APLP1/APLP2 triple knockout embryonic stem cells behave normally in vitro and in vivo: lack of evidence for a cell autonomous role of APP in neuronal differentiation. Stem Cells, 28:399-406.

2009

Patrik Verstreken*, Tomoko Ohyama*, Claire Haueter, Ron L. Habets, Y.Q. Lin, Laura E. Swan, Cindy V. Ly, Koen J.T. Venken, Pietro De Camilli and Hugo J. Bellen (2009). Tweek, an evolutionarily conserved protein, is required for synaptic vesicle recycling. Neuron, 63:203-215. *equal contribution.

[Preview in Nature Chemical Biology]

Ching Man Choi,* Sven Vilain*, Sofie Van Kelst, Marion Langen, Nathalie De Geest, Jiekun Yan, Patrik Verstreken and Bassem A. Hassan. (2009). Conditional mutagenesis in Drosophila. Science, 324:54. *equal contribution.

Vanessa A. Morais, Patrik Verstreken^, Anne Röthig, Joél Smet, An Snellinx, Dominik M. Haddad, Wim Mandemakers, Rudy Van Coster, Wolfgang Wurst, Luca Scorrano and Bart De Strooper^. (2009). Parkinson’s disease mutations in PINK1 affect Complex I activity in mitochondria. EMBO Molecular Medicine, 1:99-101.

^ corresponding authors.

[CloseUp in EMBO Molecular Medicine]

Claire L. Simpson*, Robin Lemmens*, Katarzyna Miskiewicz,Wendy J. Broom,Valerie K. Hansen, Paul W.J. van Vught, John E. Landers,

Peter Sapp, Ludo Van Den Bosch, Joanne Knight, Benjamin M. Neale, Martin R. Turner, Jan H. Veldink, Roel A. Ophoff, Vineeta B. Tripathi1, Ana Beleza, Meera N. Shah, Petroula Proitsi, Annelies Van Hoecke, Peter Carmeliet, H. Robert Horvitz, P. Nigel Leigh, Christopher E. Shaw, Leonard H. van den Berg, Pak C. Sham, John F. Powell, Patrik Verstreken, Robert H. Brown Jr., Wim Robberecht, Ammar Al-Chalabi. (2009). Variants of the RNA polymerase II component ELP3 are associated with motor neuron degeneration. Human and Molecular Genetics, 18: 472-481.*equal contribution.

2008

Jaroslaw Kasprowicz*, Sabine Kuenen*, Ron Habets, Katarzyna Miskiewicz, Liesbet Smitz and Patrik Verstreken. (2008). Inactivation of clathrin heavy chain inhibits synaptic recycling but allows bulk membrane uptake. The Journal of Cell Biology, 182:1007-1016.*equal contribution.

Koen J.T. Venken*, Jaroslaw Kasprowicz*, Sabine Kuenen, Jiekun Yan, Bassem Hassan and Patrik Verstreken. (2008). Recombineering-mediated tagging of Drosophila genomic constructs for in vivo localization and acute protein inactivation. Nucleic Acids Research, 36:e114, 1-9. *equal contribution.

Updated: Nov 24, 2011

Book Chapters

Jan R. Slabbaert, Thang Manh Khuong and Patrik Verstreken (2012). Phosphoinositides at the neuromuscular junction of Drosophila melanogaster: a genetic approach. In Lipids Methods in Cell Biology. eds. M. Wenk, G. Di Paolo. Vol 108.

Melissa Vos*, Elsa Lauwers* and Patrik Verstreken. (2010). Synaptic mitochondria and organization of vesicle pools in health and disease. Frontiers in Synaptic Neuroscience: Synaptic Vesicle Pool Organization, eds. R. Renden and M. Hodge. 2, art. 139. *equal contribution.

Ron L.P. Habets and Patrik Verstreken. (2010). Acute inactivation of synaptic proteins. In Drosophila Neurobiology Methods: A Laboratory Course manual. 533p, eds. S. Waddel, M. Freeman and B. Zhang. 393-406.

Liesbet Smitz and Patrik Verstreken. (2008). Synaptic vesicle endocytosis. In Molecular Mechanisms of Neurotransmitter Release. 347p, ed. Z. Wang. 207-238

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